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kw.\*:("Tetrahydroisoquinoline")

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Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffoldAL-HORANI, Rami A; MEHTA, Akul Y; DESAI, Umesh R et al.European journal of medicinal chemistry. 2012, Vol 54, pp 771-783, issn 0223-5234, 13 p.Article

Asymmetric synthesis and cytotoxicity of (―)-saframycin A analoguesWENFANG DONG; WEI LIU; ZHENG YAN et al.European journal of medicinal chemistry. 2012, Vol 49, pp 239-244, issn 0223-5234, 6 p.Article

1-Methyl-1,2,3,4-tetrahydroisoquinoline protects against rotenone-induced mortality and biochemical changes in rat brainANTKIEWICZ-MICHALUK, Lucyna; KAROLEWICZ, Beata; ROMANSKA, Irena et al.European journal of pharmacology. 2003, Vol 466, Num 3, pp 263-269, issn 0014-2999, 7 p.Article

In vivo bioconversion of tetrahydroisoquinoline by recombinant coclaurine N-methyltransferaseMORISHIGE, Takashi; CHOI, Kum-Boo; SATO, Fumihiko et al.Bioscience, biotechnology, and biochemistry. 2004, Vol 68, Num 4, pp 939-941, issn 0916-8451, 3 p.Article

Disposition of 1,2,3,4,-tetrahydroisoquinoline in the brain of male Wistar and Dark Agouti ratsLORENC-KOCI, Elzbieta; WOJCIKOWSKI, Jacek; KOT, Marta et al.Brain research. 2004, Vol 996, Num 2, pp 168-179, issn 0006-8993, 12 p.Article

THE EFFECT OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE CONCENTRATION AND SPECIES DIFFERENCE ON THE INHIBITORY POTENCY OF SK & F 64139.PENDLETON RG; WEINER G; JENKINS B et al.1977; RES. COMMUNIC. CHEM. PATHOL. PHARMACOL.; U.S.A.; DA. 1977; VOL. 17; NO 2; PP. 201-213; BIBL. 9 REF.Article

1-Βenzyl-1,2,3,4-tetrahydroisoquinoline passes through the blood-brain barrier of rat brain : An in vivo microdialysis studyYARU SONG; YANGZHENG FENG; LEBLANC, Michael H et al.Neuroscience letters. 2006, Vol 395, Num 1, pp 63-66, issn 0304-3940, 4 p.Article

Construction of drug screening cell model and application to new compounds inhibiting FITC-fibrinogen binding to CHO cells expressing human αIIbβ3JIE YANG; JIA YAO; JIE CHEN et al.European journal of pharmacology. 2009, Vol 618, Num 1-3, pp 1-8, issn 0014-2999, 8 p.Article

Bis-tetrahydroisoquinoline derivatives: Structure analysis of the three stereoisomers of 1,1'-(propane-1,3-diyl)-bis-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline)WOUTERS, Johan; ELASAAD, Kossay; NORBERG, Bernadette et al.European journal of medicinal chemistry. 2010, Vol 45, Num 7, pp 3240-3244, issn 0223-5234, 5 p.Article

A phase I pharmacokinetic study of PM00104 (Zalypsis®) administered as a 24-h intravenous infusion every 3 weeks in patients with advanced solid tumorsCAPDEVILA, J; CLIVE, S; FERNANDEZ TERUEL, C et al.Cancer chemotherapy and pharmacology. 2013, Vol 71, Num 5, pp 1247-1254, issn 0344-5704, 8 p.Article

2,3-Diamino acid modifying 3S-tetrahydroisoquinoline-3-carboxylic acids: Leading to a class of novel agents with highly unfolded conformation, selective in vitro anti-platelet aggregation and potent in vivo anti-thrombotic activityXIAOYI ZHANG; WEI WANG; SHENLING CHENG et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 4, pp 1536-1554, issn 0968-0896, 19 p.Article

1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitorsKLOPFENSTEIN, Sean R; EVDOKIMOV, Artem G; FARMER, Julie A et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 6, pp 1574-1578, issn 0960-894X, 5 p.Article

Neuroprotective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on cultured rat mesencephalic neurons in the presence or absence of various neurotoxinsKOTAKE, Yaichiro; TAGUCHI, Ryota; OKUDA, Katsuhiro et al.Brain research. 2005, Vol 1033, Num 2, pp 143-150, issn 0006-8993, 8 p.Article

An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regionsNAGATSU, T; YOSHIDA, M.Neuroscience letters. 1988, Vol 87, Num 1-2, pp 178-182, issn 0304-3940Article

Chiral aziridine-2-carboxylates: versatile precursors for functionalized tetrahydroisoquinoline (THIQ) containing heterocyclesKYU MYUNG LEE; JONG CHAN KIM; KANG, Philjun et al.Tetrahedron (Oxford. Print). 2012, Vol 68, Num 3, issn 0040-4020, 778, 883-893 [12 p.]Article

Enantioselective synthesis of 1-vinyltetrahydroisoquinolines via Pd-catalyzed intramolecular asymmetric allylic amination reactionsCHIEN, Chih-Wei; SHI, Ce; LIN, Chi-Feng et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 35, issn 0040-4020, 6407, 6513-6523 [12 p.]Article

Tetrahydroisoquinoline-Based N-Oxides as Chiral Organocatalysts for the Asymmetric Allylation of AldehydesNAICKER, Tricia; ARVIDSSON, Per I; KRUGER, Hendrik G et al.European journal of organic chemistry (Print). 2011, Num 34, pp 6923-6932, issn 1434-193X, 10 p.Article

Sigma-1 ligands: Tic-hydantoin as a key pharmacophoreTOUSSAINT, Marion; MOUSSET, Deborah; FOULON, Catherine et al.European journal of medicinal chemistry. 2010, Vol 45, Num 1, pp 256-263, issn 0223-5234, 8 p.Article

Synthesis and antitumor activity of simplified ecteinascidin-saframycin analogsLIU, Zhan-Zhu; YE WANG; TANG, Ye-Feng et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 5, pp 1282-1285, issn 0960-894X, 4 p.Article

EFFECTS OF TETRAHYDROPAPAVEROLINE AND SALSOLINOL ON CEREBRAL MONOAMINE METABOLISM AND THEIR INTERACTIONS WITH PSYCHOPHARMACOLOGICAL DRUGSAWAZI N; GULDBERG HC.1979; ARCH. (NAUNYN-SCHMIEDEBERG'S) PHARMACOL.; DEU; DA. 1979; VOL. 306; NO 2; PP. 135-146; BIBL. 49 REF.Article

STUDIES ON SK & F 29661, AN ORGAN-SPECIFIC INHIBITOR OF PHENYLETHANOLAMINE N-METHYLTRANSFERASEPENDLETON RG; GESSNER G; WEINER G et al.1979; J. PHARMARCOL. EXPER. THERAPEUT.; USA; DA. 1979; VOL. 208; NO 1; PP. 24-30; BIBL. 15 REF.Article

The interaction of tetrahydroisoquinoline derivatives with antinociceptive action of morphine and oxotremorine in miceVETULANI, J; PAVONE, F; PRZEWŁOCKA, B et al.Journal of neural transmission. 2003, Vol 110, Num 11, pp 1205-1213, issn 0300-9564, 9 p.Article

Comparative anticonvulsant activity of N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives in rodentsFERRERI, Guido; CHIMIRRI, Alba; RUSSO, Emilio et al.Pharmacology, biochemistry and behavior. 2004, Vol 77, Num 1, pp 85-94, issn 0091-3057, 10 p.Article

A One-Pot, Three-Component Approach to Functionalised Tetrahydroisoquinolines Using Domino Heck―aza-Michael ReactionsPRIEBBENOW, Daniel L; PFEFFER, Frederick M; STEWART, Scott G et al.European journal of organic chemistry (Print). 2011, Num 9, pp 1632-1635, issn 1434-193X, 4 p.Article

Chiral capillary electrophoresis―mass spectrometry of tetrahydroisoquinoline-derived neurotoxins: Observation of complex stereoisomerismHAO WU; BAIQING YUAN; LIU, Yi-Ming et al.Journal of chromatography. 2011, Vol 1218, Num 20, pp 3118-3123, issn 0021-9673, 6 p.Article

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